BDBM50315445 4,6-dihydroxy-2-((5-methoxy-2-methyl-1H-indol-3-yl)methylene)benzofuran-3(2H)-one::CHEMBL1088835

SMILES COc1ccc2[nH]c(C)c(\C=C3/Oc4cc(O)cc(O)c4C3=O)c2c1

InChI Key InChIKey=XMUQISMCKNWEHC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50315445   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315445(4,6-dihydroxy-2-((5-methoxy-2-methyl-1H-indol-3-yl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315445(4,6-dihydroxy-2-((5-methoxy-2-methyl-1H-indol-3-yl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315445(4,6-dihydroxy-2-((5-methoxy-2-methyl-1H-indol-3-yl...)
Affinity DataIC50: 25nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed