BDBM50315788 2-(4-(1-Isopropyl-piperidin-3-yl)phenyl)-1H-benzimidazole-4-carboxamide::CHEMBL1092223

SMILES CC(C)N1CCCC(c2ccc(-c3nc4c(C(N)=O)cccc4[nH]3)cc2)C1

InChI Key InChIKey=QTONZRQJLGKQRC-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50315788   

TargetPoly [ADP-ribose] polymerase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315788BDBM50315788(2-(4-(1-Isopropyl-piperidin-3-yl)phenyl)-1H-benzim...)
Affinity DataKi:  12nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315788BDBM50315788(2-(4-(1-Isopropyl-piperidin-3-yl)phenyl)-1H-benzim...)
Affinity DataKi:  23nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315788BDBM50315788(2-(4-(1-Isopropyl-piperidin-3-yl)phenyl)-1H-benzim...)
Affinity DataEC50:  26nMAssay Description:Inhibition of PARP1 in human C41 cells by FITC-conjugated DAPI stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed