BDBM50316288 CHEMBL1098300::Methyl [4-(4-Morpholin-4-yl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl]carbamate

SMILES COC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(-c3ccccc3)c2n1

InChI Key InChIKey=LBUAXQMQACBZHH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316288   

LigandPNGBDBM50316288(CHEMBL1098300 | Methyl [4-(4-Morpholin-4-yl-1-phen...)
Affinity DataIC50:  493nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316288(CHEMBL1098300 | Methyl [4-(4-Morpholin-4-yl-1-phen...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed