BDBM50316291 CHEMBL1095281::N-Methyl-N-[4-(4-morpholin-4-yl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl]acetamide

SMILES CN(C(C)=O)c1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(-c3ccccc3)c2n1

InChI Key InChIKey=FGNWNPNHRQNBPI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316291   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316291(N-Methyl-N-[4-(4-morpholin-4-yl-1-phenyl-1H-pyrazo...)
Affinity DataIC50: 480nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
LigandPNGBDBM50316291(N-Methyl-N-[4-(4-morpholin-4-yl-1-phenyl-1H-pyrazo...)
Affinity DataIC50: 792nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed