BDBM50316489 CHEMBL1095989::N-(4-{1-Ethyl-4-[2-({[3-(4-methyl-1-piperazinyl)propyl]amino}-methyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1H-pyrazol-3-yl}phenyl)-N'-phenylurea

SMILES CCn1cc(-c2ccnc3[nH]c(CNCCCN4CCN(C)CC4)cc23)c(-c2ccc(NC(=O)Nc3ccccc3)cc2)n1

InChI Key InChIKey=RDIZFHYTFVBBCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316489   

TargetAurora kinase B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316489BDBM50316489(N-(4-{1-Ethyl-4-[2-({[3-(4-methyl-1-piperazinyl)pr...)
Affinity DataIC50: 83nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316489BDBM50316489(N-(4-{1-Ethyl-4-[2-({[3-(4-methyl-1-piperazinyl)pr...)
Affinity DataIC50: 5.11E+3nMAssay Description:Inhibition of human Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed