BDBM50316778 CHEMBL1099339::tert-Butyl-2-{5-(4-hydroxyphenethoxy)-1-{5-[4-(methylthio)phenyl]pentyl}-1H-indole-3-yl}ethyl carbamate

SMILES CSc1ccc(CCCCCn2cc(CCNC(=O)OC(C)(C)C)c3cc(OCCc4ccc(O)cc4)ccc23)cc1

InChI Key InChIKey=YUDFSLOBZJIACN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50316778   

TargetVascular endothelial growth factor receptor 2(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316778(tert-Butyl-2-{5-(4-hydroxyphenethoxy)-1-{5-[4-(met...)
Affinity DataIC50: 5.00E+4nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316778(tert-Butyl-2-{5-(4-hydroxyphenethoxy)-1-{5-[4-(met...)
Affinity DataIC50: 5.00E+4nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316778(tert-Butyl-2-{5-(4-hydroxyphenethoxy)-1-{5-[4-(met...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of VEGFR3 after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316778(tert-Butyl-2-{5-(4-hydroxyphenethoxy)-1-{5-[4-(met...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of EGFR after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed