BDBM50317181 2-[8-(beta-Carboline-2-ium-2-yl)octyl]-beta-carboline-2-ium dibromide::CHEMBL1088654

SMILES C(CCCC[n+]1ccc2c(c1)[nH]c1ccccc21)CCC[n+]1ccc2c(c1)[nH]c1ccccc21

InChI Key InChIKey=OBSHKXBSFJPWFE-UHFFFAOYSA-P

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50317181   

TargetCholinesterase(Horse)
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317181(2-[8-(beta-Carboline-2-ium-2-yl)octyl]-beta-carbol...)
Affinity DataIC50: 76nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317181(2-[8-(beta-Carboline-2-ium-2-yl)octyl]-beta-carbol...)
Affinity DataIC50: 113nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317181(2-[8-(beta-Carboline-2-ium-2-yl)octyl]-beta-carbol...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317181(2-[8-(beta-Carboline-2-ium-2-yl)octyl]-beta-carbol...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2B receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L13-E6 cells assesse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed