BDBM50317182 2-[12-(beta-Carboline-2-ium-2-yl)dodecyl]-beta-carboline-2-ium dibromide::CHEMBL1088377

SMILES C(CCCCCC[n+]1ccc2c(c1)[nH]c1ccccc21)CCCCC[n+]1ccc2c(c1)[nH]c1ccccc21

InChI Key InChIKey=VCJGRMVHAYBWRI-UHFFFAOYSA-P

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50317182   

TargetCholinesterase(Horse)
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317182(2-[12-(beta-Carboline-2-ium-2-yl)dodecyl]-beta-car...)
Affinity DataIC50: 22nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317182(2-[12-(beta-Carboline-2-ium-2-yl)dodecyl]-beta-car...)
Affinity DataIC50: 86nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50317182(2-[12-(beta-Carboline-2-ium-2-yl)dodecyl]-beta-car...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317182(2-[12-(beta-Carboline-2-ium-2-yl)dodecyl]-beta-car...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2B receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L13-E6 cells assesse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317182(2-[12-(beta-Carboline-2-ium-2-yl)dodecyl]-beta-car...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50317182(2-[12-(beta-Carboline-2-ium-2-yl)dodecyl]-beta-car...)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed