BDBM50317188 2-[9-(beta-Carboline-2-ium-2-yl)nonyl]-beta-carboline-2-ium dibromide::CHEMBL1088655

SMILES C(CCCC[n+]1ccc2c(c1)[nH]c1ccccc21)CCCC[n+]1ccc2c(c1)[nH]c1ccccc21

InChI Key InChIKey=OBGGTWXFOZQOKR-UHFFFAOYSA-P

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50317188   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317188(2-[9-(beta-Carboline-2-ium-2-yl)nonyl]-beta-carbol...)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2B receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L13-E6 cells assesse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317188(2-[9-(beta-Carboline-2-ium-2-yl)nonyl]-beta-carbol...)
Affinity DataIC50:  125nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317188(2-[9-(beta-Carboline-2-ium-2-yl)nonyl]-beta-carbol...)
Affinity DataIC50:  41nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317188(2-[9-(beta-Carboline-2-ium-2-yl)nonyl]-beta-carbol...)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed