BDBM50317742 3-methyl-4-(4'-methyl-3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1098850

SMILES Cc1ccc(cc1S(C)(=O)=O)-c1cccc(c1)-c1c(C)cnc2c(cccc12)C(F)(F)F

InChI Key InChIKey=APHRFSGOWKZUGE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317742   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50317742(3-methyl-4-(4'-methyl-3'-(methylsulfonyl)biphenyl-...)
Affinity DataEC50:  175nMAssay Description:Agonist activity at human recombinant LXRbeta ligand binding domain in HuH7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50317742(3-methyl-4-(4'-methyl-3'-(methylsulfonyl)biphenyl-...)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]T0901317 from LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50317742(3-methyl-4-(4'-methyl-3'-(methylsulfonyl)biphenyl-...)
Affinity DataIC50:  3.20nMAssay Description:Displacement of [3H]T0901317 from LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed