BDBM50317987 CHEMBL1096072::N-(4-amino-4'-(trifluoromethyl)biphenyl-3-yl)benzamide

SMILES Nc1ccc(cc1NC(=O)c1ccccc1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=SXNSPGPBTATFRJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317987   

TargetHistone deacetylase 2(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317987(CHEMBL1096072 | N-(4-amino-4'-(trifluoromethyl)bip...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50317987(CHEMBL1096072 | N-(4-amino-4'-(trifluoromethyl)bip...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed