BDBM58491 5-[2,3-bis(chloranyl)phenoxy]-6-chloranyl-2-methylsulfanyl-1H-benzimidazole::6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole::6-chloro-5-(2,3-dichlorophenoxy)-2-methylsulfanyl-1H-benzimidazole::CHEMBL1086440::MLS001424101::SMR000466357::TRICLABENDAZOLE::cid_50248

SMILES CSc1nc2cc(Cl)c(Oc3cccc(Cl)c3Cl)cc2[nH]1

InChI Key InChIKey=NQPDXQQQCQDHHW-UHFFFAOYSA-N

Data  3 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 58491   

TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM58491(5-[2,3-bis(chloranyl)phenoxy]-6-chloranyl-2-methyl...)
Affinity DataEC50:  4.70E+3nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTransthyretin(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM58491(5-[2,3-bis(chloranyl)phenoxy]-6-chloranyl-2-methyl...)
Affinity DataIC50:  3.50E+3nMAssay Description:Stabilization of TTR V3OM mutant (unknown origin) assessed as acid-mediated protein aggregation inhibition ratio incubated for 1 week by absorbance m...More data for this Ligand-Target Pair
TargetCruzipain(Trypanosoma cruzi)
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM58491(5-[2,3-bis(chloranyl)phenoxy]-6-chloranyl-2-methyl...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine preincubated for 5 mins before substrate addition by fluorescence assay in absence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM58491(5-[2,3-bis(chloranyl)phenoxy]-6-chloranyl-2-methyl...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine preincubated for 5 mins before substrate addition by fluorescence assay in presence of 0.01% Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed