BDBM50318934 2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-1-yl)-N-methylacetamide::CHEMBL1083754::PF-02367982

SMILES CNC(=O)Cn1cc(C2CC2)c(Oc2ccc(cc2)C#N)c1C1CC1

InChI Key InChIKey=AALHNBNOUAEYHF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50318934   

TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50: 47nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells by alkaline phosphatase releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of estrogen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed