BDBM50320952 6-(2-tert-butyl-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl)quinoxaline::CHEMBL401570::SB-525334

SMILES Cc1cccc(n1)-c1nc([nH]c1-c1ccc2nccnc2c1)C(C)(C)C

InChI Key InChIKey=DKPQHFZUICCZHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50320952   

TargetTGF-beta receptor type-1(Human)
Minzu University of China

Curated by ChEMBL
LigandPNGBDBM50320952(SB-525334 | 6-(2-tert-butyl-5-(6-methylpyridin-2-y...)
Affinity DataIC50: 14nMAssay Description:Inhibition of GST tagged TbetaR-1 (unknown origin) in the presence of 33 P-gamma ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Minzu University of China

Curated by ChEMBL
LigandPNGBDBM50320952(SB-525334 | 6-(2-tert-butyl-5-(6-methylpyridin-2-y...)
Affinity DataIC50: 14nMAssay Description:Inhibition of TGFbetaR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetTGF-beta receptor type-1(Human)
Minzu University of China

Curated by ChEMBL
LigandPNGBDBM50320952(SB-525334 | 6-(2-tert-butyl-5-(6-methylpyridin-2-y...)
Affinity DataIC50: 162nMAssay Description:Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed