BDBM50322919 4-(4-(3-(4-methylpiperazin-1-yl)propoxy)-3-(trifluoromethyl)phenyl)pyrimidine-2-carbonitrile::CHEMBL1209146

SMILES CN1CCN(CCCOc2ccc(cc2C(F)(F)F)-c2ccnc(n2)C#N)CC1

InChI Key InChIKey=LZLJBBHMBQJUSF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322919   

TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322919(4-(4-(3-(4-methylpiperazin-1-yl)propoxy)-3-(triflu...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322919(4-(4-(3-(4-methylpiperazin-1-yl)propoxy)-3-(triflu...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed