BDBM50325874 CHEMBL1224285::endo-5-((1R,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-yloxy)picolinamide

SMILES NC(=O)c1ccc(O[C@@H]2C[C@@H]3CC[C@H](C2)N3Cc2ccccc2)cn1

InChI Key InChIKey=IHHVZLHQDBHJII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325874   

TargetKappa-type opioid receptor(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325874(endo-5-((1R,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in HEK cells assessed as inhibition of dynorphin A-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed