BDBM50326615 2-Amino-4-(N-methyl-m-bromoanilino)-6-(2,5-dimethoxybenzyl)-pyrrolo[2,3-d]pyrimidine::CHEMBL1254444

SMILES COc1ccc(OC)c(Cc2cc3c(nc(N)nc3[nH]2)N(C)c2cccc(Br)c2)c1

InChI Key InChIKey=MFHUUPOUXJRWOX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326615   

TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50326615(2-Amino-4-(N-methyl-m-bromoanilino)-6-(2,5-dimetho...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PDGFRbeta expressed in human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50326615(2-Amino-4-(N-methyl-m-bromoanilino)-6-(2,5-dimetho...)
Affinity DataIC50: 1.44E+5nMAssay Description:Inhibition of EGFR expressed in human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50326615(2-Amino-4-(N-methyl-m-bromoanilino)-6-(2,5-dimetho...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of VEGFR2 expressed in human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed