BDBM50328348 CHEMBL1257917::diethyl 7-butyl-2-morpholino-4-phenylpyrrolo[1,2-b]pyridazine-5,6-dicarboxylate

SMILES CCCCc1c(C(=O)OCC)c(C(=O)OCC)c2c(cc(nn12)N1CCOCC1)-c1ccccc1

InChI Key InChIKey=XWOCGCUYJMJYHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328348   

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328348(diethyl 7-butyl-2-morpholino-4-phenylpyrrolo[1,2-b...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328348(diethyl 7-butyl-2-morpholino-4-phenylpyrrolo[1,2-b...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed