BDBM50328525 CHEMBL1259221::N-{(2S,3S)-1-[(2S)-2-(5,6-Dichloro-1H-benzimidazol-2-yl)-pyrrolidin-1-yl]-1-oxo-3-phenylbutan-2-yl}-2-hydroxy-2-methylpropanamide

SMILES C[C@H]([C@H](NC(=O)C(C)(C)O)C(=O)N1CCC[C@H]1c1nc2cc(Cl)c(Cl)cc2[nH]1)c1ccccc1

InChI Key InChIKey=CGMWWRBYQTVZEX-WVFSVQOHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50328525   

TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328525(CHEMBL1259221 | N-{(2S,3S)-1-[(2S)-2-(5,6-Dichloro...)
Affinity DataIC50:  98nMAssay Description:Inhibition of mouse PrCP by FRET in presence of 1% mouse serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328525(CHEMBL1259221 | N-{(2S,3S)-1-[(2S)-2-(5,6-Dichloro...)
Affinity DataIC50:  29nMAssay Description:Inhibition of mouse PrCP by FRETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328525(CHEMBL1259221 | N-{(2S,3S)-1-[(2S)-2-(5,6-Dichloro...)
Affinity DataIC50:  59nMAssay Description:Inhibition of human PrCP by FRET in presence of 1% mouse serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328525(CHEMBL1259221 | N-{(2S,3S)-1-[(2S)-2-(5,6-Dichloro...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human PrCP by FRETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed