BDBM50331694 (2R,3R,4S)-3-acetamido-2-((1R,2R)-3-benzamido-1,2-dihydroxypropyl)-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylate::CHEMBL1289198

SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CNC(=O)c1ccccc1)C(O)=O

InChI Key InChIKey=ZIGQEQQUVHQXEH-OVJXPFRRSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50331694   

TargetSialidase-3(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50331694((2R,3R,4S)-3-acetamido-2-((1R,2R)-3-benzamido-1,2-...)
Affinity DataIC50:  3.20E+5nMAssay Description:Inhibition of human neuraminidase 3 assessed as inhibition of 4-methylumbelliferyl-alpha-D-glucopyranoside hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase-4(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50331694((2R,3R,4S)-3-acetamido-2-((1R,2R)-3-benzamido-1,2-...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of MBP-fused human NEU4 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase-3(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50331694((2R,3R,4S)-3-acetamido-2-((1R,2R)-3-benzamido-1,2-...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of N-terminal MBP-fused human NEU3 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase-2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50331694((2R,3R,4S)-3-acetamido-2-((1R,2R)-3-benzamido-1,2-...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of N-terminal MBP-fused human NEU2 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase-1(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50331694((2R,3R,4S)-3-acetamido-2-((1R,2R)-3-benzamido-1,2-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human His6-tagged NEU1 expressed in HEK293 cells using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed