BDBM50331754 CHEMBL1288516::methyl 3,5-bis(trifluoromethyl)benzyl((5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl)methyl)carbamate

SMILES COC(=O)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)Cc1cc(ccc1-c1cc(ccc1OC)C(C)C)C(F)(F)F

InChI Key InChIKey=FLZUSMRJISRMKG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50331754   

TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50331754(CHEMBL1288516 | methyl 3,5-bis(trifluoromethyl)ben...)
Affinity DataIC50:  108nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50331754(CHEMBL1288516 | methyl 3,5-bis(trifluoromethyl)ben...)
Affinity DataIC50:  126nMAssay Description:Inhibition of CETP-mediated BODIPY-labeled cholesteryl ester transfer after 45 mins by FRET analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50331754(CHEMBL1288516 | methyl 3,5-bis(trifluoromethyl)ben...)
Affinity DataIC50:  126nMAssay Description:Inhibition of human recombinant CETP-mediated cholesteryl ester transfer activity after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed