BDBM50333085 (R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,14-dioxa-5-azabenzocyclododecen-7-yl)hexanoic acid hydroxyamide::CHEMBL1631911

SMILES ONC(=O)CCCCCC1OCCCCCCOc2ccccc2NC1=O

InChI Key InChIKey=WCTLKUHJSQSAOJ-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50333085   

TargetHistone deacetylase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50:  878nMAssay Description:Inhibition of human HDAC5 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50:  738nMAssay Description:Inhibition of human HDAC7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50:  560nMAssay Description:Inhibition of human HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of human HDAC2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50:  176nMAssay Description:Inhibition of human HDAC3 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50:  564nMAssay Description:Inhibition of human HDAC11 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human HDAC4 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50:  687nMAssay Description:Inhibition of human HDAC9 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human HDAC6 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50:  683nMAssay Description:Inhibition of human HDAC10 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human HDAC8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed