BDBM50334883 3-ethyl-5-(piperidin-3-yl)pyrazolo[1,5-a]pyrimidin-7-amine::CHEMBL1643241

SMILES CCc1cnn2c(N)cc(nc12)C1CCCNC1

InChI Key InChIKey=WBFNTXRPIPRJPF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334883   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334883(3-ethyl-5-(piperidin-3-yl)pyrazolo[1,5-a]pyrimidin...)
Affinity DataIC50: 270nMAssay Description:Inhibition of CDK2/cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334883(3-ethyl-5-(piperidin-3-yl)pyrazolo[1,5-a]pyrimidin...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of recombinant His-CHK1 expressed in baculovirus after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed