BDBM50335954 CHEMBL1668898::Sodium [2'-[(cyclopropanecarbonyl-ethyl-amino)-methyl]-4'-(6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetate
SMILES CCOc1ccc(cn1)-c1ccc(c(CN(CC)C(=O)C2CC2)c1)-c1cc(CC([O-])=O)ccc1OC
InChI Key InChIKey=NNHVHOSSHPGFHJ-UHFFFAOYSA-M
Data 18 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50335954
Affinity DataIC50: 31nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation counting in presence of 0.2 % HSAMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]iloprost from IP receptor in human 293 cell membraneMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Amira Pharmaceuticals
Curated by ChEMBL
Amira Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of PPAR gammaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape change after 4 hrs by flow cytometryMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX-1More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human CYP3A4 by time-dependent inhibition assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Amira Pharmaceuticals
Curated by ChEMBL
Amira Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of PPAR alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape change by flow cytometryMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX-2More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Amira Pharmaceuticals
Curated by ChEMBL
Amira Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of PPAR betaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.67E+4nMAssay Description:Displacement of [3H]PGD2 from DP1 in human platelet membraneMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]SQ-29548 from TP receptor in human platelet membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation countingMore data for this Ligand-Target Pair