BDBM503362 (5M)-6-amino-5-(2,3- dichlorophenyl)-2-{[(3S,4R)-3- fluoropiperidin-4-yl]amino}- pyrimidine-4-carboxamide::US11033547, Compound 64::US11696916, Compound 64

SMILES NC(=O)c1nc(N[C@@H]2CCNC[C@@H]2F)nc(N)c1-c1cccc(Cl)c1Cl

InChI Key InChIKey=YEJQZFAYBWSJCU-VHSXEESVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 503362   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM503362((5M)-6-amino-5-(2,3- dichlorophenyl)-2-{[(3S,4R)-3...)
Affinity DataIC50:  1.00E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM503362((5M)-6-amino-5-(2,3- dichlorophenyl)-2-{[(3S,4R)-3...)
Affinity DataIC50:  1.00E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent