BDBM50337534 4-methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl benzoate::CHEMBL1682829

SMILES CN1CCOc2cc(OC(=O)c3ccccc3)cnc12

InChI Key InChIKey=DTNUUARSOITKQB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337534   

TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337534(4-methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7...)
Affinity DataEC50:  12.3nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in human HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed