BDBM50339381 (+/-)-3-(4-chlorophenyl)-3-((1-(hydroxymethyl)cyclopropyl)methoxy)-2-(naphthalen-1-ylmethyl)isoindolin-1-one::CHEMBL1688286

SMILES OCC1(COC2(N(Cc3cccc4ccccc34)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1

InChI Key InChIKey=HSOYSLMQKONCSZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339381   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339381BDBM50339381((+/-)-3-(4-chlorophenyl)-3-((1-(hydroxymethyl)cycl...)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed