BDBM50339395 (+/-)-2-((1-(4-chlorophenyl)-1-((1-(hydroxymethyl)cyclopropyl)methoxy)-3-oxoisoindolin-2-yl)methyl)pyridine 1-oxide::CHEMBL1688300

SMILES OCC1(COC2(N(Cc3cccc[n+]3[O-])C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1

InChI Key InChIKey=ZBGYICCGFBQSAI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339395   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339395BDBM50339395((+/-)-2-((1-(4-chlorophenyl)-1-((1-(hydroxymethyl)...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed