BDBM50339425 4-((1-(4-Chlorophenyl)-1-hydroxy-3-oxoisoindolin-2-yl)methyl)benzoic acid::CHEMBL1688160

SMILES OC(=O)c1ccc(CN2C(=O)c3ccccc3C2(O)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=ZPVWVZMIDHYDQP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339425   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339425BDBM50339425(4-((1-(4-Chlorophenyl)-1-hydroxy-3-oxoisoindolin-2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed