BDBM503395 (5P)-2-[(3aR,6aS)-3a- (aminomethyl)-octahydro- cyclopenta[c]pyrrol-2-yl]-6-amino-5- (2,3-dichlorophenyl)-pyrimidine-4- carboxamide::US11033547, Compound 98::US11033547, Compound 99
SMILES NC[C@@]12CCC[C@@H]1CN(C2)c1nc(N)c(-c2cccc(Cl)c2Cl)c(n1)C(N)=O
InChI Key InChIKey=OYZALVSWJSKCSW-GIGQVBGESA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 503395
Affinity DataIC50: 3.70E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair