BDBM50340434 (4-(1H-pyrazol-3-yl)piperidin-1-yl)(3,4-dihydroquinolin-1(2H)-yl)methanone::CHEMBL1761847

SMILES O=C(N1CCC(CC1)c1ccn[nH]1)N1CCCc2ccccc12

InChI Key InChIKey=RKYLSXVZXXFFEN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340434   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50340434((4-(1H-pyrazol-3-yl)piperidin-1-yl)(3,4-dihydroqui...)
Affinity DataIC50:  127nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50340434((4-(1H-pyrazol-3-yl)piperidin-1-yl)(3,4-dihydroqui...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed