BDBM50340523 5,5-dimethyl-1-((2-(4-methylpiperazin-1-yl)pyridin-4-yl)methyl)-3-(4-(trifluoromethylthio)phenyl)imidazolidine-2,4-dione::CHEMBL1762158

SMILES CN1CCN(CC1)c1cc(CN2C(=O)N(C(=O)C2(C)C)c2ccc(SC(F)(F)F)cc2)ccn1

InChI Key InChIKey=LPSFUUIFEVVEDP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340523   

TargetInsulin-like growth factor 1 receptor(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50340523(5,5-dimethyl-1-((2-(4-methylpiperazin-1-yl)pyridin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF-induced autophosphosphorylation of GST-tagged human IGF1R expressed in SF21 cells by time resolved-fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed