BDBM50341142 (E)-3-(4-Hydroxy-3,5-dimethoxy-phenyl)-acrylic acid::3-(3,4,5-trimethoxyphenyl)acrylic acid::3-(4-hydroxy-3,5-dimethoxyphenyl)-(E)-2-propenoic acid::3-(4-hydroxy-3,5-dimethoxyphenyl)acrylic acid::CHEMBL109341::SINAPINATE::Sinapic acid

SMILES COc1cc(\C=C\C(O)=O)cc(OC)c1O

InChI Key InChIKey=PCMORTLOPMLEFB-ONEGZZNKSA-N

Data  4 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50341142   

TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50341142((E)-3-(4-Hydroxy-3,5-dimethoxy-phenyl)-acrylic aci...)
Affinity DataIC50: >3.51E+5nMAssay Description:Inhibition of mushroom tyrosinase after 25 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-glucosidase MAL62(Saccharomyces cerevisiae)TBA
LigandPNGBDBM50341142((E)-3-(4-Hydroxy-3,5-dimethoxy-phenyl)-acrylic aci...)
Affinity DataIC50:  1.45E+5nMAssay Description:Inhibition of yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 10 min before substrate addition and ...More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50341142((E)-3-(4-Hydroxy-3,5-dimethoxy-phenyl)-acrylic aci...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of COX2 after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50341142((E)-3-(4-Hydroxy-3,5-dimethoxy-phenyl)-acrylic aci...)
Affinity DataIC50:  3.92E+4nMAssay Description:Inhibition of COX1 after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed