BDBM50342196 1-[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazol-3-ylmethyl]-3-(4-trifluoromethyl-phenyl)-urea::CHEMBL1766293

SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(CNC(=O)Nc2ccc(cc2)C(F)(F)F)cc1-c1ccccc1

InChI Key InChIKey=GBRFBXBSJSEFIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342196   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342196(1-[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazo...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342196(1-[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed