BDBM50342197 1-[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazol-3-ylmethyl]-3-(3-trifluoromethyl-phenyl)-urea::CHEMBL1766294

SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(CNC(=O)Nc2cccc(c2)C(F)(F)F)cc1-c1ccccc1

InChI Key InChIKey=OBYAQBHBZOVQED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342197   

TargetBifunctional epoxide hydrolase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50342197(1-[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazo...)
Affinity DataIC50: 72nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50342197(1-[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazo...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed