BDBM50342912 6-(benzo[d][1,3]dioxol-5-yl)-N-methyl-N-((5-methyl-1,3,4-oxadiazol-2-yl)methyl)quinazolin-4-amine::CHEMBL1437638

SMILES CN(Cc1nnc(C)o1)c1ncnc2ccc(cc12)-c1ccc2OCOc2c1

InChI Key InChIKey=CKEWXVJUPNKAPF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50342912   

TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342912(6-(benzo[d][1,3]dioxol-5-yl)-N-methyl-N-((5-methyl...)
Affinity DataIC50: 45nMAssay Description:Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342912(6-(benzo[d][1,3]dioxol-5-yl)-N-methyl-N-((5-methyl...)
Affinity DataIC50: 98nMAssay Description:Inhibition of Clk1 kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342912(6-(benzo[d][1,3]dioxol-5-yl)-N-methyl-N-((5-methyl...)
Affinity DataIC50: 120nMAssay Description:Inhibition of Dyrk1A kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342912(6-(benzo[d][1,3]dioxol-5-yl)-N-methyl-N-((5-methyl...)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of Dyrk1B kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342912(6-(benzo[d][1,3]dioxol-5-yl)-N-methyl-N-((5-methyl...)
Affinity DataIC50: 3.12E+3nMAssay Description:Inhibition of Clk2 kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342912(6-(benzo[d][1,3]dioxol-5-yl)-N-methyl-N-((5-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Clk3 kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed