BDBM50344214 3-((3-phenyl-1H-pyrazol-4-yl)methylene)indolin-2-one::CHEMBL1778710

SMILES O=C1Nc2ccccc2C1=Cc1c[nH]nc1-c1ccccc1

InChI Key InChIKey=RINGOEHWKXCHGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344214   

TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50344214(3-((3-phenyl-1H-pyrazol-4-yl)methylene)indolin-2-o...)
Affinity DataIC50:  2.72E+3nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344214(3-((3-phenyl-1H-pyrazol-4-yl)methylene)indolin-2-o...)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed