BDBM50344271 (R)-quinuclidin-3-yl phenyl(thiophen-3-ylmethyl)carbamate::CHEMBL1779034

SMILES O=C(O[C@H]1CN2CCC1CC2)N(Cc1ccsc1)c1ccccc1

InChI Key InChIKey=JZXJMFOSRNVGHQ-SFHVURJKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50344271   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50344271((R)-quinuclidin-3-yl phenyl(thiophen-3-ylmethyl)ca...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50344271((R)-quinuclidin-3-yl phenyl(thiophen-3-ylmethyl)ca...)
Affinity DataIC50:  4.70nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50344271((R)-quinuclidin-3-yl phenyl(thiophen-3-ylmethyl)ca...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed