BDBM50344277 (R)-quinuclidin-3-yl bis(thiophen-2-ylmethyl)carbamate::CHEMBL1779040

SMILES O=C(O[C@H]1CN2CCC1CC2)N(Cc1cccs1)Cc1cccs1

InChI Key InChIKey=VRZIYMYSNOVVOK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50344277   

TargetMuscarinic acetylcholine receptor M1(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50344277((R)-quinuclidin-3-yl bis(thiophen-2-ylmethyl)carba...)
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50344277((R)-quinuclidin-3-yl bis(thiophen-2-ylmethyl)carba...)
Affinity DataIC50: 5.90nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50344277((R)-quinuclidin-3-yl bis(thiophen-2-ylmethyl)carba...)
Affinity DataIC50: 22.7nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed