BDBM50345812 3-((S)-1-(dimethylamino)ethyl)phenylmethyl((R)-1-phenylpropan-2-yl)carbamate hydrochloride::CHEMBL1784958

SMILES C[C@H](Cc1ccccc1)N(C)C(=O)Oc1cccc(c1)[C@H](C)N(C)C

InChI Key InChIKey=QGKSWUZOCNWHHA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345812   

TargetAcetylcholinesterase(Human)
Sention

Curated by ChEMBL
LigandPNGBDBM50345812(3-((S)-1-(dimethylamino)ethyl)phenylmethyl((R)-1-p...)
Affinity DataIC50: 302nMAssay Description:Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sention

Curated by ChEMBL
LigandPNGBDBM50345812(3-((S)-1-(dimethylamino)ethyl)phenylmethyl((R)-1-p...)
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed