BDBM50349191 CHEMBL1807642

SMILES Cc1cccc2scc(Cn3c(SCCCC(O)=O)nc4ccccc34)c12

InChI Key InChIKey=YSOMBHFITHOMPW-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50349191   

TargetCathepsin G(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349191(CHEMBL1807642)
Affinity DataIC50:  52nMAssay Description:Inhibition of human cathepsin G using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349191(CHEMBL1807642)
Affinity DataIC50:  22nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair