BDBM503575 US11034670, Ex. 15

SMILES Cc1ccc2c(=O)[nH]c(CCC(=O)N3CCN(c4ccc(C#N)cn4)CC3)nc2c1

InChI Key InChIKey=ICZVYYLYOGLKDU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503575   

TargetPoly [ADP-ribose] polymerase 1(Human)
Mitobridge

US Patent
LigandChemical structure of BindingDB Monomer ID 503575BDBM503575(US11034670, Ex. 15)
Affinity DataIC50: 196nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent