BDBM50357718 CHEMBL1916168

SMILES CCC(C)[C@]1(CCN([C@@H](CCc2ccccc2)C(=O)N[C@@H](Cc2cc(F)cc(F)c2)[C@H](O)[C@H]2C[C@H](CN2)OCc2ccc(F)cc2)C1=O)NC(C)=O

InChI Key InChIKey=PYFPQNUDNPPKCN-OGBHQHSVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357718   

TargetBeta-secretase 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50357718(CHEMBL1916168)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing swedish mutant APPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50357718(CHEMBL1916168)
Affinity DataIC50:  10nMAssay Description:Inhibition of BACE1 by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed