BDBM503592 6-[4-[3-(6-fluoro-4-oxo-3H-quinazolin-2-yl)propanoyl]-3-(hydroxymethyl)piperazin-1-yl]pyridine-3-carbonitrile::US11034670, Ex. 32

SMILES OCC1CN(CCN1C(=O)CCc1nc2ccc(F)cc2c(=O)[nH]1)c1ccc(cn1)C#N

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503592   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Mitobridge

US Patent
LigandPNGBDBM503592(6-[4-[3-(6-fluoro-4-oxo-3H-quinazolin-2-yl)propano...)
Affinity DataIC50:  5nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent