BDBM50359502 CHEMBL1230845::HYDROXYAMPHETAMINE

SMILES C[C@@H](N)Cc1ccc(O)cc1

InChI Key InChIKey=GIKNHHRFLCDOEU-SSDOTTSWSA-N

Data  4 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50359502   

TargetTrace amine-associated receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359502(CHEMBL1230845 | HYDROXYAMPHETAMINE)
Affinity DataEC50:  3.16E+3nMAssay Description:Activation of C-terminal HA epitope tagged human TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein, Galpha16 by cAMP accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Macaca mulatta)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359502(CHEMBL1230845 | HYDROXYAMPHETAMINE)
Affinity DataEC50:  424nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359502(CHEMBL1230845 | HYDROXYAMPHETAMINE)
Affinity DataEC50:  5.65E+3nMAssay Description:Activation of mouse TAAR1 expressed in human HEK293 cells assessed as accumulation of [3H]cAMP after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359502(CHEMBL1230845 | HYDROXYAMPHETAMINE)
Affinity DataEC50:  60nMAssay Description:Activation of rat TAAR1 expressed in HEK293 cells assessed as accumulation of [3H]cAMP after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed