BDBM50359895 CHEMBL261267

SMILES [O-][N+](=O)c1cccc(\C=C2/S\C(NC2=O)=N/c2nsc3ccccc23)c1

InChI Key InChIKey=JWLRMBKRMUREIB-ZROIWOOFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50359895   

TargetCollagenase 3(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50359895(CHEMBL261267)
Affinity DataIC50:  5.59E+4nMAssay Description:Inhibition of MMP13 catalytic domain (unknown origin) assessed as reduction in hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate measured f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Alexander Technological Education Institute Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50359895(CHEMBL261267)
Affinity DataIC50:  7.94E+4nMAssay Description:Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Alexander Technological Education Institute Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50359895(CHEMBL261267)
Affinity DataIC50:  1.26E+5nMAssay Description:Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed