BDBM50360453 CHEMBL1934626

SMILES Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C#Cc1ccc(CN2CCCC2)c(F)c1

InChI Key InChIKey=MCIKCKGVVBUURA-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50360453   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)
Affinity DataIC50: 62nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)
Affinity DataIC50: 190nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360453(CHEMBL1934626)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of INSRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360453(CHEMBL1934626)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed