BDBM50360582 CHEMBL1933345

SMILES Oc1ccc(cc1)-c1nc(Nc2cccc(Cl)c2)nc2nc[nH]c12

InChI Key InChIKey=DVJXBMQCLHDFIV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50360582   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360582(CHEMBL1933345)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of PDK1 using [gamma33P]-ATP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360582(CHEMBL1933345)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360582(CHEMBL1933345)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of PDK1 assessed as [gamma-33P]ATP incorporation into substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360582(CHEMBL1933345)
Affinity DataIC50:  830nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360582(CHEMBL1933345)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK2 using RbING as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360582(CHEMBL1933345)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed