BDBM50361233 CHEMBL1934523

SMILES COCCCS(=O)(=O)c1ccc(cc1)-c1ccc(CCN2CCC[C@H]2C)cc1

InChI Key InChIKey=ADRZQEOBUFIYAZ-UHFFFAOYSA-N

Data  2 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50361233   

TargetHistamine H3 receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361233(CHEMBL1934523)
Affinity DataIC50: 0.700nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361233(CHEMBL1934523)
Affinity DataKi:  0.700nMAssay Description:Displacement of N-[3H]-methylhistamine from histamine H3 receptor in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361233(CHEMBL1934523)
Affinity DataKi:  4.20nMAssay Description:Binding affinity to human cloned histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361233(CHEMBL1934523)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERG by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361233(CHEMBL1934523)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361233(CHEMBL1934523)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361233(CHEMBL1934523)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361233(CHEMBL1934523)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361233(CHEMBL1934523)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed