BDBM50362709 CHEMBL1939782

SMILES COc1cc(C)c2nc3[nH]nc(C)c3c(N3CCNCC3)c2c1

InChI Key InChIKey=LRBQTFPUUPFJQW-UHFFFAOYSA-N

Data  2 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50362709   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362709(CHEMBL1939782)
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant human PDE10A using [3H]cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362709(CHEMBL1939782)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of recombinant human PDE5A using [3H]cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362709(CHEMBL1939782)
Affinity DataIC50:  858nMAssay Description:Inhibition of recombinant human PDE10A using [3H]cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362709(CHEMBL1939782)
Affinity DataIC50:  320nMAssay Description:Inhibition of CK1deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed